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產(chǎn)品型號：50ul;100ul

更新時間：2024-12-26

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品牌	其他品牌	純度	100
貨號	bs-0483R	規(guī)格	50u;100ul
供貨周期	現(xiàn)貨	主要用途	科研實(shí)驗(yàn)
應(yīng)用領(lǐng)域	醫(yī)療衛(wèi)生,化工,生物產(chǎn)業(yè),綜合

基本信息

產(chǎn)品編號	bs-0483R
英文名稱	Rabbit Anti-Centromeric histone H3-like protein-2 antibody
中文名稱	組蛋白H3樣抗體
別名	centromere-specific H3 variant protein; Centromeric histone H3-like protein 2; Centromeric histone H3-like protein-2; cenp-A; A4PIF1_BRAJU.
產(chǎn)品類型	植物抗體
組蛋白H3樣抗體研究領(lǐng)域	腫瘤免疫學(xué) 發(fā)育生物學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子植物
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應(yīng)	(predicted: Brassica juncea)
產(chǎn)品應(yīng)用	IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
理論分子量	20kDa
細(xì)胞定位	細(xì)胞核
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from Brassica juncea Centromeric histone H3-like protein-2: 3-19/178
亞型	IgG
純化方法	affinity purified by Protein A
緩沖液	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
產(chǎn)品介紹	Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome, the basic subunit of chromatin. Histone modifications regulate DNA transcription, repair, recombination, and replication. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications (the "histone code" hypothesis). Trimethylation of histone H3 on Lys9 (H3K9me3) is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely via acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1Alpha/Beta. The enzymes responsible for H3K9me3 formation are SUV39H1 and SUV39H2.